Prp – Platelet-Rich Plasma

PRP Therapy with Exosomes in Milan with Dr. Giovani Buzzaccarini: Regenerative Medicine for Intimate Wellbeing and Fertility.

PRP – Platelet-Rich Plasma is an autologous, non-hormonal regenerative therapy that uses growth factors from your own blood to repair tissues and improve elasticity, hydration and vascularization of the vulva and vagina.

It can also be supplemented with exosomes, which represent the new frontier in regenerative medicine.

Why choose PRP (and why choose Dr. Buzzaccarini in Milan)

Autologous, safe, non-hormonal

Also recommended when local estrogens are not indicated

Targeted regenerative action

Growth factors: collagen, elastin, vascularization, trophism

Outpatient and quick

Micro-injections/local instillation, with same-day return to normal activities

Structured treatment plan

Usually 1–2 sessions every 3–4 weeks; follow-up sessions depending on clinical outcome

Milan, a network of excellence

Medical practice in the Cadorna area and partner clinics for diagnostics/assisted reproduction

Treatment Areas

PRP for Vulvar Lichen Sclerosus

Treatment Goal:
Reduction of itching, burning, and fissuring, and improvement of tissue elasticity.

 

PRP for Vulvovaginal atrophy (VVA)

Treatment Goal:
Increased hydration and comfort, and reduction of dyspareunia and recurrent irritation.

Endometrial PRP for Thin Endometrium and Recurrent Pregnancy Loss

Treatment Goal:
Enhancement of endometrial thickness and receptivity, supporting implantation and continuation of pregnancy.

PRP for Vulvar/Vaginal Scars

Treatment Goal:
Softening and remodeling of scar tissue (postpartum or post-surgical), with pain relief and functional improvement.

How PRP with exosomes is performed

Blood collection (20 ml) and centrifugation in dedicated tubes

PRP preparation (controlled platelet concentration)

Targeted application: vulvovaginal micro-injections / intrauterine infusion for the endometrium.

Exosome enrichment

Post-procedure instructions: refrain from intercourse for 24-48 hours (vulvo-vaginal) or as per the endometrial protocol

Timing and results: initial benefits often seen within 1–2 weeks, maximum response at 4-8 weeks; personalized maintenance plan.

Dr. Giovanni Buzzaccarini (Milan)

Gynecologist specialized in regenerative medicine and PRP therapies applied to intimate well-being and fertility. In Milan, he develops integrated treatment plans: PRP with exosomes + standard therapies (e.g., topical steroids for lichen, moisturizers/laser for atrophic vulvovaginitis) and, when necessary, in synergy with ART for thin endometrium and recurrent pregnancy loss.

Values: clinical rigor, clear and science-based information, personalized treatment plans, follow-up and results monitoring.

Frequently Asked Questions (FAQ)

Only minimal discomfort: local anesthesia and fine needles; mild temporary soreness afterwards.

Usually 1-2 sessions every 3–4 weeks; maintenance sessions based on clinical response and goals.

First benefits in 1–2 weeks; peak results between 4-8 weeks after the treatment cycle.

Yes. Non-hormonal and autologous: a useful option for patients with contraindications to local estrogen.

In aesthetic medicine, exosomes are tiny extracellular vesicles used to regenerate skin and tissue by stimulating collagen and elastin production. They have healing and anti-inflammatory effects.

Book an appointment in Milan with Dr. Giovanni Buzzaccarini

Medical assessment, PRP protocol definition and session scheduling.